Keynote Lecture

Prof. Dr. Berthold Langguth
Klinik und Poliklinik für Psychiatrie und Psychotherapie der Universität Regensburg
am Bezirksklinikum Regensburg

Induction of neuroplasticity in tinnitus patients following therapeutic interventions

Neuroscientfic research in the last decades has identified specific alterations of brain activity and brain structure in patients with chronic tinnitus. Moreover specific aspects of tinnitus, such as tinnitus laterality, tinnitus duration or tinnitus distress are related to specific alterations in brain networks.

Based on these findings several interventions have been developed that aim at "normalizing" these tinnitus-related changes in the brain.

The identification of neuroplastic changes induced by therapeutic interventions can help to better identify neurobiological mechanisms of specific treatments and thus contribute to further develop these treatment approaches.

In this talk an overview is given about our current knowledge of tinnitus-related changes in the brain. It is further discussed to which extent these alterations reflect tinnitus pathology and to which extent these changes reflect compensatory mechanisms of the brain.